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What is Codeine Phosphate?

Codeine Phosphate is a versatile opiate used for:

  • Pain Relief: Treats mild to moderate pain.
  • Cough Medicine: Effective for managing cough.
  • Diarrhea Treatment: Helps control diarrhea and diarrhea-predominant irritable bowel syndrome.

How Codeine Phosphate Works

  • Onset of Action: Starts working within 30 minutes.
  • Peak Effect: Reaches maximum effect in two hours.
  • Duration: Effects last for about 4 to 6 hours.

Common Combinations for Enhanced Effect

  • Paracetamol (Acetaminophen)
  • NSAIDs: Such as aspirin or ibuprofen.

Usage and Administration

  • Form: Oral tablets.
  • Dosage: Typically prescribed in 15mg doses. Follow your doctor’s instructions for precise usage.

Important Considerations

  • Tolerance and Dependence: Risk of dependence and withdrawal symptoms with prolonged use.
  • Mental Health Risks: Monitor for signs of addiction and breathing difficulties.
  • Metabolism: Broken down by the liver into morphine, with varying speed depending on genetics.

History and Availability

  • Discovery: Discovered in 1832 by Pierre Jean Robiquet.
  • Production: In 2013, 361,000 kilograms produced globally.
  • Cost:
    • Developing World: $0.04 to $0.29 per dose.
    • United States: About $1 per dose.
  • Natural Occurrence: Makes up about 2% of opium.

Benefits of Codeine Phosphate

  • Pain Management: Effective for treating mild to moderate pain.
  • Cough Relief: Useful as a cough suppressant.
  • Diarrhea Control: Treats severe diarrhea and related conditions.

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