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What is Dilaudid (Hydromorphone)?

Dilaudid, also known as Hydromorphone or dihydromorphinone, is a potent centrally acting pain medication from the opioid class. It is derived from morphine and is similar to hydrocodone in relation to codeine. In medical terms, Hydromorphone is an opioid analgesic, and legally, it is classified as a narcotic.

Key Benefits of Dilaudid:

  • Powerful Pain Relief: Dilaudid is highly effective for managing severe pain, especially in hospital settings.
  • Quick Absorption: While it is often administered intravenously due to low oral bioavailability, sublingual (under the tongue) administration is also effective.
  • High Solubility: Hydromorphone is more water-soluble than morphine, allowing for concentrated solutions in smaller volumes.

Usage and Administration:

Hydromorphone is commonly used intravenously in hospitals due to its rapid and efficient pain-relieving properties. For oral administration, sublingual use is preferred over swallowing because of better bioavailability, though absorption is still relatively slow.


  • High Potency: Hydromorphone is much stronger than morphine, so caution is required to avoid overdose, especially if mistaken for other narcotics.
  • Solubility: Hydromorphone hydrochloride is highly soluble in water, making it suitable for creating concentrated solutions.

Potential Side Effects:

  • Nausea and Vomiting
  • Constipation
  • Drowsiness and Dizziness
  • Respiratory Depression

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Disclaimer: Dilaudid is a prescription medication and should only be used under the supervision of a healthcare professional. Misuse can lead to dependence and other serious health risks.

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