BUY UR-144 EXPERIENCE ONLINE

Buy UR-144 Online

Buy UR-144 online from a trusted source specializing in high-quality synthetic cannabinoids. UR-144, also known as TMCP-018, KM-X1, MN-001, or YX-17, was developed by Abbott Laboratories. It acts as a selective full agonist of the peripheral cannabinoid receptor CB2, distinguishing itself with lower affinity for the psychoactive CB1 receptor.

Key Features of UR-144

UR-144 exhibits a high affinity for the CB2 receptor, boasting a Ki of 1.8 nM, while its affinity for the CB1 receptor is significantly lower with a Ki of 150 nM. Scientific studies have identified UR-144 as capable of producing effects such as bradycardia and hypothermia in animal models, indicating mild cannabinoid-like activity.

Chemical Structure and Related Compounds

Chemically related to other 2,2,3,3-tetramethylcyclopropyl synthetic cannabinoids like A-796,260 and A-834,735, UR-144 features a distinctive substitution on the 1-position of its indole core. Unlike similar compounds, UR-144 replaces its 1-pentyl group with alkylheterocycles such as 1-(2-morpholinoethyl) and 1-(tetrahydropyran-4-ylmethyl).

Legal Status and Regulations

UR-144 has been subject to regulatory actions in various countries. For instance, in the United Kingdom, the Advisory Council on the Misuse of Drugs (ACMD) recommended its inclusion under generic prohibition legislation in October 2012. Subsequently, the UK Home Office classified UR-144 as a Class B drug under The Misuse of Drugs Act 1971 (Amendment) Order 2013.

Global Impact and Bans

UR-144 has been identified as an ingredient in synthetic cannabis smoking blends in New Zealand, leading to its temporary classification as a class drug and subsequent ban from sale on April 6, 2012. Similar regulatory actions have been taken in Russia, where it was also included in bans on synthetic cannabinoids.

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